HOAt CAS 39968-33-7 1-Hydroxy-7-Azabenzotriazole Peptide Coupling Reagent Purity >99.5% (HPLC) Factory

Short Description:

1-Hydroxy-7-Azabenzotriazole

Synonyms: HOAt 

CAS: 39968-33-7

Purity: >99.5% (HPLC)

White to Off-White Crystalline Powder

Peptide Coupling Reagents, High Quality 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 1-Hydroxy-7-Azabenzotriazole (HOAt) (CAS: 39968-33-7) with high quality. Ruifu Chemical supplys a series of protecting reagents and coupling reagents. Ruifu can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase HOAt Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name 1-Hydroxy-7-Azabenzotriazole  
Synonyms HOAt; 3H-[1,2,3]-Triazolo[4,5-b]pyridin-3-ol; N-Hydroxy-7-Azobenzotriazole; 7-Aza-1-Hydroxybenzotriazole
Stock Status In Stock, Commercial Scale
CAS Number 39968-33-7 
Molecular Formula C5H4N4O
Molecular Weight 136.11 g/mol
Melting Point 212.0~216.0℃ 
Density 0.973 g/mL at 20℃  
Refractive Index n20/D 1.441
Solubility in Hot NaOH  Almost Transparency  
Storage Temp.  Cool & Dry Place (2~8℃) 
COA & MSDS Available
Category   Coupling Reagents 
Brand Ruifu Chemical

Specifications:

Items Inspection Standards Results
Appearance White to Off-White Crystalline Powder Complies      
Melting Point 212.0~216.0℃ 213.0~214.0℃
Loss on Drying <0.50% 0.10% 
Purity / Analysis Method >99.5% (HPLC)  99.9% 
Clarity of Solution 0.3gram in 2 ml DMF Clear Solution  Complies      
Infrared Spectrum Consistent with Structure Complies      
1 H NMR Spectrum  Consistent with Structure Complies      
Conclusion The product has been tested & complies with the given specifications

Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

39968-33-7 - Risk and Safety:

Risk Codes
R61 - May cause harm to the unborn child
R20/21 - Harmful by inhalation and in contact with skin.
R36 - Irritating to the eyes
R5 - Heating may cause an explosion
R36/37/38 - Irritating to eyes, respiratory system and skin.
R11 - Highly Flammable
R41 - Risk of serious damage to eyes
R37/38 - Irritating to respiratory system and skin.
R22 - Harmful if swallowed
R2 - Risk of explosion by shock, friction, fire or other sources of ignition
R36/37 - Irritating to eyes and respiratory system.
Safety Description
S53 - Avoid exposure - obtain special instructions before use.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S37/39 - Wear suitable gloves and eye/face protection
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S16 - Keep away from sources of ignition.
S39 - Wear eye / face protection.
S35 - This material and its container must be disposed of in a safe way.
S36 - Wear suitable protective clothing.
S36/37 - Wear suitable protective clothing and gloves.
S28 - After contact with skin, wash immediately with plenty of soap-suds.
S15 - Keep away from heat.
UN IDs UN 1993 3/PG 3
WGK Germany 1
HS Code 2933990099
Hazard Class IRRITANT
Packing Group Ⅱ

Application:

1-Hydroxy-7-Azabenzotriazole (HOAt) (CAS: 39968-33-7) is a coupling reagent in peptide synthesis. HOAt efficiently speeds up coupling process and reduces the loss of chirality.
Coupling activator for racemization-free coupling in peptide synthesis; An additive for peptide segment coupling in in reducing the extent of configurational loss at the reactive carboxylic acid residue.
Inhibition of racemization in polypeptide condensation; also used for fragment condensation. 

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